LabCAST

In terms of clinical data from the Betaseron® trial, there was statistically significant evidence that:

  • Patients who were antibody positive after 18 months had higher relapse rates than patients who were antibody negative.
  • Patients who were antibody positive after 24 months had more enlarging lesions on their MRIs than patients who were antibody negative.
Effect of NAb (titer³ 20) on MRI in
Phase III Study
 
Mean # Gd-Enhanced lesions at Year 2
Mean # New and Enlarging T2 lesions at Year 2
Placebo
1.6
4.6
NAb-
0.6
2.8
NAb+
1.7*
4.2**
P=.06, NAb+ vs. NAb- (Wilcoxon Rank Sum Test)
**P=.28, NAb+ vs. NAb- (Wilcoxon Rank Sum Test)
Reprinted with permission from a slideshow by Dr. Timothy Vartanian.1

End of Session II. Thank you for participating. Please look for an email announcing Session III: Clinical management and the role of NAbs, in two weeks.

  
1 2 3 4 5
Your understanding of the disease or condition
How you will diagnose patients with this disorder
How you will explain the disease or condition to patients and their families
None of the above

Breaking news in genetics
Dementias
Epilepsy
Mitochondrial disorders
Movement disorders
Multiple sclerosis
Neuromuscular disorders
Pediatric disorders
More information on Athena's MS & NAbs testing services
 
Please have a local sales rep contact me
 
 
 
 
 

 

Results and Discussion
Back
NAbs Main Menu
Back

Betaseron is a registered trademark of Berlex Laboratories, Inc.